Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine

Abstract Infection of C57Bl/6 mice by pleomorphic African trypanosomes Trypanosoma brucei and T. congolense is characterized by parasitemia waves coupled with the production of systemic levels of TNF. This cytokine is known to control T. brucei growth, but also to contribute to tissue damage, shorte...

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Bibliographic Details
Main Authors: Gilles Vanwalleghem, Yannick Morias, Alain Beschin, David E. Szymkowski, Etienne Pays
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06496-2