Lipidomic approach for stratification of acute myeloid leukemia patients.

The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing membrane components but these may also alter physicochemical properties of lipid...

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Bibliographic Details
Main Authors: Adam Stefanko, Christian Thiede, Gerhard Ehninger, Kai Simons, Michal Grzybek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5313223?pdf=render