Omentin-1 Modulates Macrophage Function via Integrin Receptors αvβ3 and αvβ5 and Reverses Plaque Vulnerability in Animal Models of Atherosclerosis

Omentin-1 Modulates Macrophage Function via Integrin Receptors αvβ3 and αvβ5 and Reverses Plaque Vulnerability in Animal Models of Atherosclerosis

Backgrounds: Omentin-1 is a novel cytokine that is primarily released by the epicardial adipose tissue. Molecular structure analysis revealed that it contained a fibrinogen-like domain. Clinical studies have demonstrated that the expression of omentin-1 is tightly associated with the development of...

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Bibliographic Details
Main Authors: Xuze Lin, Yan Sun, Shiwei Yang, Mengyue Yu, Liu Pan, Jie Yang, Jiaqi Yang, Qiaoyu Shao, Jinxing Liu, Yan Liu, Yujie Zhou, Zhijian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
plaque vulnerability
adipokine
integrin
atherosclerosis
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.757926/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.757926/full

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