Inducible degradation of the Drosophila Mediator subunit Med19 reveals its role in regulating developmental but not constitutively-expressed genes

Inducible degradation of the Drosophila Mediator subunit Med19 reveals its role in regulating developmental but not constitutively-expressed genes

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The multi-subunit Mediator complex plays a critical role in gene expression by bridging enhancer-bound transcription factors and the RNA polymerase II machinery. Although experimental case studies suggest differential roles of Mediator subunits, a comprehensive view of the specific set of genes regu...

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Bibliographic Details
Main Authors: Denis Jullien, Emmanuelle Guillou, Sandra Bernat-Fabre, Adeline Payet, Henri-Marc G. Bourbon, Muriel Boube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707739/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707739/?tool=EBI

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