Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients.

Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients.

We investigated whether circulating osteopontin (OPN) could be used as a biomarker for cervical cancer. We employed a monoclonal antibody (mAb 659) specific for the unique and intact thrombin-sensitive site in OPN using an inhibition ELISA. We found significantly higher levels of OPN in 33 cervical...

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Bibliographic Details
Main Authors: Danny T M Leung, Pak-Leong Lim, Tak-Hong Cheung, Raymond R Y Wong, So-Fan Yim, Margaret H L Ng, Frankie C H Tam, Tony K H Chung, Yick-Fu Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4975440?pdf=render

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http://europepmc.org/articles/PMC4975440?pdf=render

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