Type III Gustilo–Anderson open fracture does not justify routine prophylactic Gram-negative antibiotic coverage

Abstract Postoperative surgical site infection (SSI) is common in open long bone fractures, so early administration of prophylactic antibiotics is critical to prevent SSI. However, the necessity of initial broad-spectrum coverage for Gram-positive and -negative pathogens remains unclear. The purpose...

Full description

Bibliographic Details
Main Authors: Takashi Suzuki, Takahiro Inui, Miyoshi Sakai, Keisuke Ishii, Taketo Kurozumi, Yoshinobu Watanabe
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34142-7