IFN-α armed gE elicits superior immunogenicity compared to unmodified antigens and flagellin armed gE in mice

IFN-α armed gE elicits superior immunogenicity compared to unmodified antigens and flagellin armed gE in mice

Herpes zoster (HZ) induces significant pain and discomfort, which can seriously affect the quality of life of patients. At present, there is no specific treatment for HZ, and the mosteffective HZ control is vaccination. The main obstacle to developing an effective HZ vaccine is poorly induced cellul...

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Bibliographic Details
Main Authors: Jiangang Zhang, Shaodan Peng, Fang Xu, Ying Qiao, Xiaoke Ye, Yu Guan, Xiaolong Zhao, Yueran Wang, Zhongqi Shao, Tao Zhu, Weixue Si
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Vaccine: X
Subjects:
Herpes zoster
Vaccine
Glycoprotein E
Interferon-α
Online Access:http://www.sciencedirect.com/science/article/pii/S2590136224000056

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http://www.sciencedirect.com/science/article/pii/S2590136224000056

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