A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.

Despite recent advances in clinical treatment, pancreatic cancer remains a highly lethal malignancy. In order to improve the survival rate of patients with pancreatic cancer, the development of non-invasive diagnostic methods using effective biomarkers is urgently needed. Here, we developed a highly...

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Bibliographic Details
Main Authors: Keiko Shinjo, Kazuo Hara, Genta Nagae, Takayoshi Umeda, Keisuke Katsushima, Miho Suzuki, Yoshiteru Murofushi, Yuta Umezu, Ichiro Takeuchi, Satoru Takahashi, Yusuke Okuno, Keitaro Matsuo, Hidemi Ito, Shoji Tajima, Hiroyuki Aburatani, Kenji Yamao, Yutaka Kondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233782