Design, Synthesis and Biological Evaluation of Conjugates of 3-<i>O</i>-Descladinose-azithromycin and Nucleobases against rRNA A2058G- or A2059G-Mutated Strains
Structurally unrelated antibiotics MLS<sub>B</sub> (macrolide-lincosamide-streptogramin B) compromised with clinically resistant pathogens because of the cross-resistance resulting from the structural modification of rRNA A2058. The structure–activity relationships of a novel 3-<i>...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/3/1327 |