Evaluation of the MC3R gene pertaining to body weight and height regulation and puberty development

Abstract Recent studies reported an impact of the melanocortin 3 receptor (MC3R) on the regulation of body weight, linear growth and puberty timing. Previously, allele p.44Ile of a frequent non-synonymous variant (NSV) p.Val44Ile was reported to be associated with decreased lean body mass (LBM) and...

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Bibliographic Details
Main Authors: Yiran Zheng, Luisa Sophie Rajcsanyi, Triinu Peters, Astrid Dempfle, Stefan A. Wudy, Johannes Hebebrand, Anke Hinney
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37344-1