Fasting Insulin and Risk of Overall and 14 Site-Specific Cancers: Evidence From Genetic Data

Fasting Insulin and Risk of Overall and 14 Site-Specific Cancers: Evidence From Genetic Data

ObjectiveWhether fasting insulin (FI) plays a role in cancer risk remains unclear. This study aimed to investigate the association between FI and cancer risk and to explore its potential mediator role in the association between type 2 diabetes mellitus (T2DM) and cancer.MethodsTwo-sample Mendelian r...

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Bibliographic Details
Main Authors: Han Zhang, Doudou Li, Xiaozhuan Liu, Zhongxiao Wan, Zengli Yu, Yuming Wang, Xue Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
fasting insulin
type 2 diabetes
cancer
Mendelian randomization study
polygenic risk score analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.863340/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.863340/full

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