Widespread retina and optic nerve neuroinflammation in enucleated eyes from glaucoma patients

Abstract Neuroinflammation is recognized as a key component of neurodegenerative disease. In glaucoma, a common neurodegenerative disease and the leading cause of irreversible blindness, the evidence for neuroinflammation in patients is lacking. Animal models have demonstrated significant pro-inflam...

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Bibliographic Details
Main Authors: Carola Rutigliani, James R. Tribble, Anna Hagström, Emma Lardner, Gauti Jóhannesson, Gustav Stålhammar, Pete A. Williams
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-022-01427-3