Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR‐Driven Lung Cancer

Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR‐Driven Lung Cancer

Abstract Lung cancer is the leading cause of cancer death worldwide. Vaccination against EGFR can be one of the venues to prevent lung cancer. Blocking glutamine metabolism has been shown to improve anticancer immunity. Here, the authors report that JHU083, an orally active glutamine antagonist prod...

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Bibliographic Details
Main Authors: Mofei Huang, Donghai Xiong, Jing Pan, Qi Zhang, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Luis M. Montuenga, Yian Wang, Barbara S. Slusher, Ming You
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Advanced Science
Subjects:
epidermal growth factor receptor vaccines
glutamine metabolism
JHU‐083
lung tumorigenesis
tumor immune microenvironment
Online Access:https://doi.org/10.1002/advs.202105885

Internet

https://doi.org/10.1002/advs.202105885

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