Prediction of Coreceptor Tropism in HIV-1 Subtype C in Botswana

Prediction of Coreceptor Tropism in HIV-1 Subtype C in Botswana

It remains unknown whether the C-C motif chemokine receptor type 5 (CCR5) coreceptor is still the predominant coreceptor used by Human Immunodeficiency Virus-1 (HIV-1) in Botswana, where the HIV-1 subtype C predominates. We sought to determine HIV-1C tropism in Botswana using genotypic tools, taking...

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Bibliographic Details
Main Authors: Kenanao Kotokwe, Sikhulile Moyo, Melissa Zahralban-Steele, Molly Pretorius Holme, Pinkie Melamu, Catherine Kegakilwe Koofhethile, Wonderful Tatenda Choga, Terence Mohammed, Tapiwa Nkhisang, Baitshepi Mokaleng, Dorcas Maruapula, Tsotlhe Ditlhako, Ontlametse Bareng, Patrick Mokgethi, Corretah Boleo, Joseph Makhema, Shahin Lockman, Max Essex, Manon Ragonnet-Cronin, Vlad Novitsky, Simani Gaseitsiwe, PANGEA Consortium
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
CCR5
CXCR4
R5-tropic viruses
X4-tropic viruses
HIV-1C tropism
Online Access:https://www.mdpi.com/1999-4915/15/2/403

Internet

https://www.mdpi.com/1999-4915/15/2/403

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