Studies on the Inhibition of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) by 2-(3,4-Dihydroxyphenyl)-7,8-dihydroxy-3-methoxychromen-4-one, a Flavonoid from <i>Pistacia chinensis</i>

Studies on the Inhibition of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) by 2-(3,4-Dihydroxyphenyl)-7,8-dihydroxy-3-methoxychromen-4-one, a Flavonoid from <i>Pistacia chinensis</i>

Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) regulates skeletal and soft tissue mineralization by hydrolyzing nucleotide triphosphates and cyclic nucleotides, and is involved in the modulation of immune system. In fact, ENPP1 degrades 2′,3′-cyclic GMP-AMP dinucleotide (2′,3′-cGAMP), wh...

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Bibliographic Details
Main Authors: Abdur Rauf, Zuneera Akram, Muhammad Naveed, Najla AlMasoud, Taghrid S. Alomar, Muhammad Saleem, Abdul Waheed, Giovanni Ribaudo
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Chemistry
Subjects:
ENPP1
phosphodiesterase
<i>Pistacia chinensis</i>
transilitin
flavonoids
docking
Online Access:https://www.mdpi.com/2624-8549/5/4/142

Internet

https://www.mdpi.com/2624-8549/5/4/142

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