PRMT6 activates cyclin D1 expression in conjunction with the transcription factor LEF1

Abstract The establishment of cell type specific gene expression by transcription factors and their epigenetic cofactors is central for cell fate decisions. Protein arginine methyltransferase 6 (PRMT6) is an epigenetic regulator of gene expression mainly through methylating arginines at histone H3....

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Bibliographic Details
Main Authors: Lucas Schneider, Stefanie Herkt, Lei Wang, Christine Feld, Josephine Wesely, Olga N. Kuvardina, Annekarin Meyer, Thomas Oellerich, Björn Häupl, Erhard Seifried, Halvard Bonig, Joern Lausen
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00332-z