In-silico and in-vitro analysis of novel substituted benzimidazolyl derivatives for antimycobacterial potentials targeting enoyl acyl carrier protein reductase (InhA)

Abstract Background The emergence of mutated drug-resistant strains of Mycobacterium tuberculosis has reinvigorated the development of effective chemotherapy for MDR-TB (multidrug-resistant resistance tuberculosis). Enoyl acyl carrier protein reductase (InhA) involved in the mycobacterial fatty acid...

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Main Authors: Umaa Kuppuswamy, Ravi Kumar Rajan, Arvinth Kumar, Muthiah Ramanathan
格式: 文件
语言:English
出版: SpringerOpen 2022-12-01
丛编:Future Journal of Pharmaceutical Sciences
主题:
在线阅读:https://doi.org/10.1186/s43094-022-00449-x