In-silico and in-vitro analysis of novel substituted benzimidazolyl derivatives for antimycobacterial potentials targeting enoyl acyl carrier protein reductase (InhA)
Abstract Background The emergence of mutated drug-resistant strains of Mycobacterium tuberculosis has reinvigorated the development of effective chemotherapy for MDR-TB (multidrug-resistant resistance tuberculosis). Enoyl acyl carrier protein reductase (InhA) involved in the mycobacterial fatty acid...
Main Authors: | , , , |
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格式: | 文件 |
语言: | English |
出版: |
SpringerOpen
2022-12-01
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丛编: | Future Journal of Pharmaceutical Sciences |
主题: | |
在线阅读: | https://doi.org/10.1186/s43094-022-00449-x |