Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia
Background. Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, haemoglobin S (HbS) is formed, which modifies red blood cell morphology. Intravascular haemolysis occurs, in which free Hb and free radicals degrade nitric oxide (NO) and release arginase, which reduces...
Главные авторы: | , , , , , , , , |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
Wiley
2019-01-01
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Серии: | Advances in Hematology |
Online-ссылка: | http://dx.doi.org/10.1155/2019/4397150 |