Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation

Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation

Glucagon-like peptide-1 receptor has anti-apoptotic, anti-inflammatory, and neuroprotective effects. It is now recognized that the occurrence and development of chronic pain are strongly associated with anti-inflammatory responses; however, it is not clear whether glucagon-like peptide-1 receptor re...

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Bibliographic Details
Main Authors: Shan-Shan Cui, Xiao-Bo Feng, Bing-Hong Zhang, Zhong-Yuan Xia, Li-Ying Zhan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
astrocyte; chronic pain; cognitive impairment; exendin-4; hippocampal dentate gyrus; microglia; morris water maze; neuroinflammation; spinal nerve ligation
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=7;spage=1333;epage=1339;aulast=Cui

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=7;spage=1333;epage=1339;aulast=Cui

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