Naringin ameliorates 5-fluorouracil elicited neurotoxicity by curtailing oxidative stress and iNOS/NF-ĸB/caspase-3 pathway

Naringin ameliorates 5-fluorouracil elicited neurotoxicity by curtailing oxidative stress and iNOS/NF-ĸB/caspase-3 pathway

This study evaluated the protective effects of naringin (NRG) against 5-fluorouracil (5-FU)-elicited neurotoxicity. The animals were orally administered with NRG and subsequently injected with 5-FU. Injection of 5-FU caused depression in cerebral antioxidant enzymes, including glutathione peroxidase...

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Bibliographic Details
Main Authors: Zhou Peili, Wang Zhongfang, Chen Cheng, Famurewa Ademola C., Olatunji Opeyemi Joshua
Format: Article
Language:English
Published: De Gruyter 2023-10-01
Series:Open Chemistry
Subjects:
oxidative stress
naringin
5-fluorouracil
cancer
apoptosis
inflammation
Online Access:https://doi.org/10.1515/chem-2023-0126

Internet

https://doi.org/10.1515/chem-2023-0126

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