Gold Compounds Inhibit the Ca<sup>2+</sup>-ATPase Activity of Brain PMCA and Human Neuroblastoma SH-SY5Y Cells and Decrease Cell Viability

Gold Compounds Inhibit the Ca<sup>2+</sup>-ATPase Activity of Brain PMCA and Human Neuroblastoma SH-SY5Y Cells and Decrease Cell Viability

Plasma membrane calcium ATPases (PMCA) are key proteins in the maintenance of calcium (Ca<sup>2+</sup>) homeostasis. Dysregulation of PMCA function is associated with several human pathologies, including neurodegenerative diseases, and, therefore, these proteins are potential drug target...

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Bibliographic Details
Main Authors:	Maria Berrocal, Juan J. Cordoba-Granados, Sónia A. C. Carabineiro, Carlos Gutierrez-Merino, Manuel Aureliano, Ana M. Mata
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Metals
Subjects:	gold compounds PMCA Ca<sup>2+</sup>-ATPase calcium homeostasis SH-SY5Y human neuroblastoma cells
Online Access:	https://www.mdpi.com/2075-4701/11/12/1934

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