Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy

Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy

Steady-state levels of reactive oxygen species (ROS) and oxidative damage to cellular macromolecules are increased in the rodent hippocampus during epileptogenesis. However, the role of reactive nitrogen species (RNS) in epileptogenesis remains to be explored. The goal of this study was to determine...

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Bibliographic Details
Main Authors: Kristen Ryan, Li-Ping Liang, Christopher Rivard, Manisha Patel
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Neurobiology of Disease
Subjects:
Temporal lobe epilepsy
Mitochondria
Nitrogen species
Reactive oxygen species
Posttranslational modification
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113003501

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http://www.sciencedirect.com/science/article/pii/S0969996113003501

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