Molecular Docking and Molecular Dynamic Investigations of Xanthone-Chalcone Derivatives against Epidermal Growth Factor Receptor for Preliminary Discovery of Novel Anticancer Agent

Molecular Docking and Molecular Dynamic Investigations of Xanthone-Chalcone Derivatives against Epidermal Growth Factor Receptor for Preliminary Discovery of Novel Anticancer Agent

Epidermal growth factor receptor (EGFR) is found to be overexpressed in cancer cells as it controls angiogenesis, cell signaling, and proliferation mechanisms. Therefore, EGFR has been known as a common target for the initial screening of new anticancer agents. Either xanthone or chalcone has been e...

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Bibliographic Details
Main Authors: Yehezkiel Steven Kurniawan, Ervan Yudha, Gerry Nugraha, Nela Fatmasari, Harno Dwi Pranowo, Jumina Jumina, Eti Nurwening Sholikhah
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2024-02-01
Series:Indonesian Journal of Chemistry
Subjects:
chalcone
xanthone
egfr
molecular docking
molecular dynamics
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/88449

Internet

https://jurnal.ugm.ac.id/ijc/article/view/88449

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