Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application
Background Donor lymphocyte infusion is an effective form of adoptive immunotherapy for hematologic malignancies after allogeneic stem cell transplantation. Graft-versus-host disease, however, often develops due to recognition of ubiquitously-expressed minor histocompatibility antigens. Transfer of...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Ferrata Storti Foundation
2008-10-01
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Series: | Haematologica |
Online Access: | https://haematologica.org/article/view/5035 |