Stability of magistral phage preparations before therapeutic application in patients with chronic rhinosinusitis, sepsis, pulmonary, and musculoskeletal infections

Stability of magistral phage preparations before therapeutic application in patients with chronic rhinosinusitis, sepsis, pulmonary, and musculoskeletal infections

ABSTRACT Bacteriophages have (re)gained popularity as an adjunct antibacterial therapy. On top of the self-amplifying character of phages, their titer can be influenced by several factors which could lead to reduced titers after preparation and storage. The stability of phage preparations, used for...

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Bibliographic Details
Main Authors: Saartje Uyttebroek, Laura Bessems, Willem-Jan Metsemakers, Yves Debaveye, Laura Van Gerven, Lieven Dupont, Melissa Depypere, Jeroen Wagemans, Rob Lavigne, Maya Merabishvili, Jean-Paul Pirnay, David Devolder, Isabel Spriet, Jolien Onsea
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
bacteriophages
phages
phage therapy
stability
formulation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02907-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02907-23

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