Centripetal nuclear shape fluctuations associate with chromatin condensation in early prophase

Abstract The nucleus plays a central role in several key cellular processes, including chromosome organisation, DNA replication and gene transcription. Recent work suggests an association between nuclear mechanics and cell-cycle progression, but many aspects of this connection remain unexplored. Her...

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Bibliographic Details
Main Authors: Viola Introini, Gururaj Rao Kidiyoor, Giancarlo Porcella, Pietro Cicuta, Marco Cosentino Lagomarsino
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05074-9