Cerebral aquaporin-4 expression is independent of seizures in tuberous sclerosis complex

Astrocytes serve many functions in the human brain, many of which focus on maintenance of homeostasis. Astrocyte dysfunction in Tuberous Sclerosis Complex (TSC) has long been appreciated with activation of the mTORC1 signaling pathway resulting in gliosis and possibly contributing to the very freque...

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Bibliographic Details
Main Authors: Brittany Short, Lindsay Kozek, Hannah Harmsen, Bo Zhang, Michael Wong, Kevin C. Ess, Cary Fu, Robert Naftel, Matthew M. Pearson, Robert P. Carson
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301184