LncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop

Abstract Metastasis is a bottleneck in cancer treatment. Studies have shown the pivotal roles of long noncoding RNAs (lncRNAs) in regulating cancer metastasis; however, our understanding of lncRNAs in gastric cancer (GC) remains limited. RNA-seq was performed on metastasis-inclined GC tissues to unc...

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Bibliographic Details
Main Authors: Zhen-Hua Wu, Yi-Xuan Wang, Jun-Jiao Song, Li-Qin Zhao, Yu-Jia Zhai, Yan-Fang Liu, Wei-Jian Guo
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06607-8