Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss

Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss

Osteoporosis is a systemic skeletal disease which is highly prevalent worldwide and considered to be associated with excessive bone resorption mediated by osteoclast. Osteoclast differentiation is featured by the activation of inflammation-related pathways and the generation of reactive oxygen speci...

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Bibliographic Details
Main Authors: Jia Wang, Zhong Fang, Chao Song, Honglei Kang, Qian Guo, Yimin Dong, Ya Zhang, Renpeng Peng, Hanfeng Guan, Feng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
Schisandrin B
osteoclast
osteoporosis
MAPK
NF-κB
Nrf2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01175/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01175/full

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