Differential Co-Expression Network Analysis Reveals Key Hub-High Traffic Genes as Potential Therapeutic Targets for COVID-19 Pandemic

Differential Co-Expression Network Analysis Reveals Key Hub-High Traffic Genes as Potential Therapeutic Targets for COVID-19 Pandemic

BackgroundThe recent emergence of COVID-19, rapid worldwide spread, and incomplete knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited development of therapeutic strategies. Our objective was to systematically investigate molecular regulatory mechanisms of COVID-19, using...

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Bibliographic Details
Main Authors: Aliakbar Hasankhani, Abolfazl Bahrami, Negin Sheybani, Behzad Aria, Behzad Hemati, Farhang Fatehi, Hamid Ghaem Maghami Farahani, Ghazaleh Javanmard, Mahsa Rezaee, John P. Kastelic, Herman W. Barkema
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
systems biology
systems immunology
WGCNA
hub-high traffic genes
immunopathogenesis
therapeutic targets in infectious diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.789317/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.789317/full

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