Transcriptional Down-Regulation of Major Histocompatibility Complex as a Possible Pathogenesis for Meniere's Disease

Transcriptional Down-Regulation of Major Histocompatibility Complex as a Possible Pathogenesis for Meniere's Disease

ObjectivesThis study aimed to determine the underlying pathogenesis of Meniere's disease (MD) using transcriptome analysis.MethodsTotal RNA was extracted from the peripheral blood mononuclear cells of 39 patients with MD and 39 controls. Through microarray analysis for nine patients and control...

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Bibliographic Details
Main Authors: Kwang-Dong Choi, Eun Hye Oh, Hyun Sung Kim, Hyang-Sook Kim, Ji-Yun Park, Seo Young Choi, Jae-Hwan Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neurology
Subjects:
Meniere's disease
transcriptome analysis
immune system
MHC protein
differentially expressed gene
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.938740/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.938740/full

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