Hibernating ribosomes as drug targets?

When ribosome-targeting antibiotics attack actively growing bacteria, they occupy ribosomal active centers, causing the ribosomes to stall or make errors that either halt cellular growth or cause bacterial death. However, emerging research indicates that bacterial ribosomes spend a considerable amou...

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Bibliographic Details
Main Authors: Chinenye L. Ekemezie, Sergey V. Melnikov
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1436579/full