Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock

Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock

Circadian rhythmicity in renal function suggests rhythmic adaptations in renal metabolism. To decipher the role of the circadian clock in renal metabolism, we studied diurnal changes in renal metabolic pathways using integrated transcriptomic, proteomic, and metabolomic analysis performed on control...

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Bibliographic Details
Main Authors: Yohan Bignon, Leonore Wigger, Camille Ansermet, Benjamin D. Weger, Sylviane Lagarrigue, Gabriel Centeno, Fanny Durussel, Lou Götz, Mark Ibberson, Sylvain Pradervand, Manfredo Quadroni, Meltem Weger, Francesca Amati, Frédéric Gachon, Dmitri Firsov
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-04-01
Series:The Journal of Clinical Investigation
Subjects:
Nephrology
Online Access:https://doi.org/10.1172/JCI167133

Internet

https://doi.org/10.1172/JCI167133

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