In vitro calcite crystal morphology is modulated by otoconial proteins otolin-1 and otoconin-90.

Otoconia are formed embryonically and are instrumental in detecting linear acceleration and gravity. Degeneration and fragmentation of otoconia in elderly patients leads to imbalance resulting in higher frequency of falls that are positively correlated with the incidence of bone fractures and death....

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Bibliographic Details
Main Authors: K Trent Moreland, Mina Hong, Wenfu Lu, Christopher W Rowley, David M Ornitz, James J De Yoreo, Ruediger Thalmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991680?pdf=render