Roles of the ubiquitin proteasome system in the effects of drugs of abuse

Because of its ability to regulate the abundance of selected proteins the ubiquitin proteasome system (UPS) plays an important role in neuronal and synaptic plasticity. As a result various stages of learning and memory depend on UPS activity. Drug addiction, another phenomenon that relies on neuropl...

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Bibliographic Details
Main Authors: Nicolas eMassaly, Bernard eFrancés, Lionel eMoulédous
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00099/full