Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance

Human immunodeficiency virus 1 (HIV-1) infection is a global health issue since neither a cure nor a vaccine is available. However, the highly active antiretroviral therapy (HAART) has improved the life expectancy for patients with acquired immunodeficiency syndrome (AIDS). Nucleoside reverse transc...

詳細記述

書誌詳細
主要な著者: Nicole Bertoletti, Albert H. Chan, Raymond F. Schinazi, Karen S. Anderson
フォーマット: 論文
言語:English
出版事項: MDPI AG 2020-10-01
シリーズ:Molecules
主題:
オンライン・アクセス:https://www.mdpi.com/1420-3049/25/20/4868