Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance
Human immunodeficiency virus 1 (HIV-1) infection is a global health issue since neither a cure nor a vaccine is available. However, the highly active antiretroviral therapy (HAART) has improved the life expectancy for patients with acquired immunodeficiency syndrome (AIDS). Nucleoside reverse transc...
主要な著者: | , , , |
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フォーマット: | 論文 |
言語: | English |
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MDPI AG
2020-10-01
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シリーズ: | Molecules |
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オンライン・アクセス: | https://www.mdpi.com/1420-3049/25/20/4868 |