Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics

Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics

A high HLA expression in uveal melanoma (UM) is part of the prognostically unfavorable inflammatory phenotype. We wondered whether the presence of soluble HLA (sHLA) in the aqueous humour is associated with clinical, histopathological or genetic tumour characteristics, and represents tumour HLA expr...

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Bibliographic Details
Main Authors: Annemijn P. A. Wierenga, Gülçin Gezgin, Els van Beelen, Michael Eikmans, Marijke Spruyt-Gerritse, Niels J. Brouwer, Mieke Versluis, Robert M. Verdijk, Sjoerd G. van Duinen, Marina Marinkovic, Gregorius P. M. Luyten, Martine J. Jager
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
uveal melanoma
soluble HLA
infiltrate
aqueous humour
liquid biopsies
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/11/8/1202

Internet

https://www.mdpi.com/2072-6694/11/8/1202

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