Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure

Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure

Abstract Auto-antibodies (Abs) to type I interferons (IFNs) are found in up to 25% of patients with severe COVID-19, and are implicated in disease pathogenesis. It has remained unknown, however, whether type I IFN auto-Abs are unique to COVID-19, or are also found in other types of severe respirator...

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Bibliographic Details
Main Authors: Rajani Ghale, Natasha Spottiswoode, Mark S. Anderson, Anthea Mitchell, Grace Wang, Carolyn S. Calfee, Joseph L. DeRisi, Charles R. Langelier
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Respiratory Research
Subjects:
COVID-19
Auto-antibodies
Type I interferon
Anti-interferon antibodies
Acute respiratory failure
Online Access:https://doi.org/10.1186/s12931-022-02283-4

Internet

https://doi.org/10.1186/s12931-022-02283-4

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