DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations

DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations

Over the last few years, protein-based affinity reagents have proven very helpful in cell and developmental biology. While many of these versatile small proteins can be expressed both in the intracellular and extracellular milieu in cultured cells and in living organisms, they can also be functional...

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Bibliographic Details
Main Authors: M. Alessandra Vigano, Dimitri Bieli, Jonas V. Schaefer, Roman P. Jakob, Shinya Matsuda, Timm Maier, Andreas Plückthun, Markus Affolter
Format: Article
Language:English
Published: The Company of Biologists 2018-11-01
Series:Biology Open
Subjects:
DARPins
mTFP1
Protein binder
Crystal structure
Relocalization
Online Access:http://bio.biologists.org/content/7/11/bio036749

Internet

http://bio.biologists.org/content/7/11/bio036749

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