NKG2H-Expressing T Cells Negatively Regulate Immune Responses

The biology and function of NKG2H receptor, unlike the better characterized members of the NKG2 family NKG2A, NKG2C, and NKG2D, remains largely unclear. Here, we show that NKG2H is able to associate with the signaling adapter molecules DAP12 and DAP10 suggesting that this receptor can signal for cel...

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Bibliographic Details
Main Authors: Daniela Dukovska, Daniel Fernández-Soto, Mar Valés-Gómez, Hugh T. Reyburn
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00390/full