The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: <i>Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases</i>

The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: <i>Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases</i>

Mitochondria, which generate ATP through aerobic respiration, also have important noncanonical functions. Mitochondria are dynamic organelles, that engage in fission (division), fusion (joining) and translocation. They also regulate intracellular calcium homeostasis, serve as oxygen-sensors, regulat...

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Bibliographic Details
Main Authors: Pierce Colpman, Asish Dasgupta, Stephen L. Archer
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
pulmonary arterial hypertension
apoptosis
mitophagy
cancer
mitotic fission
mitochondrial dynamics protein of 49 kDa (MiD49)
Online Access:https://www.mdpi.com/2073-4409/12/14/1897

Internet

https://www.mdpi.com/2073-4409/12/14/1897

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