Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression

<p>Abstract</p> <p>Background</p> <p>In HIV-infected T lymphocytes, NF-κB/Rel transcription factors are major elements involved in the activation of LTR-dependent transcription from latency. Most NF-κB heterodimer p65/p50 is sequestered as an inactive form in the cytopl...

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Bibliographic Details
Main Authors: Mittelbrunn Maria, Rullas Joaquín, López-Huertas María, Coiras Mayte, Alcamí José
Format: Article
Language:English
Published: BMC 2007-08-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/56