Donor selection for KIR alloreactivity is associated with superior survival in haploidentical transplant with PTCy

Donor selection for KIR alloreactivity is associated with superior survival in haploidentical transplant with PTCy

With the continuous increase in the use of haploidentical donors for transplantation, the selection of donors becomes increasingly important. Haploidentical donors have been selected primarily based on clinical characteristics, while the effects of killer cell immunoglobulin-like receptors (KIRs) on...

Full description

Bibliographic Details
Main Authors: Jun Zou, Piyanuch Kongtim, Samer A. Srour, Uri Greenbaum, Johannes Schetelig, Falk Heidenreich, Henning Baldauf, Brandt Moore, Supawee Saengboon, Yudith Carmazzi, Gabriela Rondon, Qing Ma, Katayoun Rezvani, Elizabeth J. Shpall, Richard E. Champlin, Stefan O. Ciurea, Kai Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
haplo-HSCT
NK cell alloreactivity
KIR
donor selection
overall survival
progression-free survival
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033871/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033871/full

Similar Items