Combined computational analysis and cytology show limited depth osteogenic effect on bone defects in negative pressure wound therapy

Background: The treatment of bone defects remains a clinical challenge. The effect of negative pressure wound therapy (NPWT) on osteogenesis in bone defects has been recognized; however, bone marrow fluid dynamics under negative pressure (NP) remain unknown. In this study, we aimed to examine the ma...

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Bibliographic Details
Main Authors: Xiu-Hong Huang, Li-Qin Zheng, Yue-Xing Dai, Shao-Nan Hu, Wan-Chen Ning, Si-Min Li, Yue-Guang Fan, Zi-Ling Lin, Shao-Hong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1056707/full