Blockade of CCR5 suppresses paclitaxel-induced peripheral neuropathic pain caused by increased deoxycholic acid

Summary: Paclitaxel leads to peripheral neuropathy (paclitaxel-induced peripheral neuropathy [PIPN]) in approximately 50% of cancer patients. At present, there are no effective treatment strategies for PIPN, the mechanisms of which also remain unclear. In this study, we performed microbiome and meta...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Shanshan Zhong, Fangxi Liu, Rashid Giniatullin, Jukka Jolkkonen, Yong Li, Zhike Zhou, Xinyu Lin, Chang Liu, Xiuchun Zhang, Zhouyang Liu, Cheng Lv, Qianqian Guo, Chuansheng Zhao
Format: Artykuł
Język:English
Wydane: Elsevier 2023-11-01
Seria:Cell Reports
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Dostęp online:http://www.sciencedirect.com/science/article/pii/S2211124723013980