RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated β-catenin signaling in cholangiocarcinoma

RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated β-catenin signaling in cholangiocarcinoma

Abstract Background Cholangiocarcinoma (CCA) comprises a heterogeneous group of biliary tract cancer. Our previous CCA mutation pattern study focused on genes in the post-transcription modification process, among which the alternative splicing factor RBM10 captured our attention. However, the roles...

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Bibliographic Details
Main Authors: Jiang Chang, Yaodong Zhang, Tao Zhou, Qian Qiao, Jijun Shan, Yananlan Chen, Wangjie Jiang, Yirui Wang, Shuochen Liu, Yuming Wang, Yue Yu, Changxian Li, Xiangcheng Li
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
RBM10
Mutation
Alternative splicing
ASPM
Cholangiocarcinoma
Online Access:https://doi.org/10.1186/s13046-024-03030-x

Internet

https://doi.org/10.1186/s13046-024-03030-x

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