Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis

Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis

Development of multiple myeloma is preceded by precursor conditions. Here, the authors use single cell RNA-sequencing of plasma cells from patients across disease stages to identify genomic signatures present even at the earliest stages of disease.

Bibliographic Details
Main Authors: Rebecca Boiarsky, Nicholas J. Haradhvala, Jean-Baptiste Alberge, Romanos Sklavenitis-Pistofidis, Tarek H. Mouhieddine, Oksana Zavidij, Ming-Chieh Shih, Danielle Firer, Mendy Miller, Habib El-Khoury, Shankara K. Anand, François Aguet, David Sontag, Irene M. Ghobrial, Gad Getz
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33944-z

Internet

https://doi.org/10.1038/s41467-022-33944-z

Similar Items