The FBXW7-binding sites on FAM83D are potential targets for cancer therapy

The FBXW7-binding sites on FAM83D are potential targets for cancer therapy

Abstract Increasing evidence shows the oncogenic function of FAM83D in human cancer, but how FAM83D exerts its oncogenic function remains largely unclear. Here, we investigated the importance of FAM83D/FBXW7 interaction in breast cancer (BC). We systematically mapped the FBXW7-binding sites on FAM83...

Full description

Bibliographic Details
Main Authors: Xiaoyu Jiang, Yuli Wang, Lulu Guo, Yige Wang, Tianshu Miao, Lijuan Ma, Qin Wei, Xiaoyan Lin, Jian-Hua Mao, Pengju Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Breast Cancer Research
Subjects:
FBXW7
FAM83D
Ubiquitination and degradation
Breast cancer
Metastasis
Chemotherapy
Online Access:https://doi.org/10.1186/s13058-024-01795-9

Internet

https://doi.org/10.1186/s13058-024-01795-9

Similar Items