Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons
Abstract Small humanin-like peptide 2 (SHLP2) is a mitochondrial-derived peptide implicated in several biological processes such as aging and oxidative stress. However, its functional role in the regulation of energy homeostasis remains unclear, and its corresponding receptor is not identified. Here...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-40082-7 |