The ability to form homodimers is essential for RDM1 to function in RNA-directed DNA methylation.

RDM1 (RNA-DIRECTED DNA METHYLATION1) is a small plant-specific protein required for RNA-directed DNA methylation (RdDM). RDM1 interacts with RNA polymerase II (Pol II), ARGONAUTE4 (AGO4), and the de novo DNA methyltransferase DOMAINS REARRANGED METHYLTRANSFERASE2 (DRM2) and binds to methylated singl...

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Bibliographic Details
Main Authors: Taku Sasaki, Zdravko J Lorković, Shih-Chieh Liang, Antonius J M Matzke, Marjori Matzke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912163?pdf=render